Burn-Redeems on Manifold contracts utilize a “true” burn, meaning that the burned tokens will be destroyed on the blockchain and effectively cease to exist instead of simply being sent to the BurnAddress. The total on-chain supply for the burnable token will decrease with every burn.
Some non-Manifold contracts, however, don't have a burn() function. For these contracts, the tokens will be sent to the 0xdead address, and will still exist without reducing the collection supply. You'll know if this is the case for a token if it says "Limited Burn Support" after you input the contract address.